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Salvatore Antonaci Selected Research

LY2109761

7/2011Kinase activation profile associated with TGF-β-dependent migration of HCC cells: a preclinical study.
2/2010Down-regulation of connective tissue growth factor by inhibition of transforming growth factor beta blocks the tumor-stroma cross-talk and tumor progression in hepatocellular carcinoma.
10/2009Inhibition of transforming growth factor beta receptor I kinase blocks hepatocellular carcinoma growth through neo-angiogenesis regulation.

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Salvatore Antonaci Research Topics

Disease

15Neoplasms (Cancer)
09/2011 - 01/2002
13Hepatocellular Carcinoma (Hepatoma)
09/2011 - 02/2002
8Chronic Hepatitis C
02/2011 - 10/2004
7Neoplasm Metastasis (Metastasis)
07/2011 - 02/2002
3Fibrosis (Cirrhosis)
01/2012 - 08/2005
3Hepatitis C
02/2011 - 11/2004
3Infections
07/2010 - 09/2005
2Liver Cirrhosis (Hepatic Cirrhosis)
04/2011 - 08/2010
2Carcinogenesis
08/2010 - 05/2008
2Hepatitis
05/2006 - 01/2005
2Breast Neoplasms (Breast Cancer)
05/2004 - 03/2002
1Lymphoma (Lymphomas)
08/2011
1Malaria
08/2011
1Acute malaria
08/2011
1Hypergammaglobulinemia (Hyperimmunoglobulinemia)
08/2011
1Inflammation (Inflammations)
08/2010
1Carcinoma (Carcinomatosis)
05/2009
1Disease Progression
05/2008
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
11/2005
1Bronchopneumonia
09/2005
1Systemic Scleroderma (Systemic Sclerosis)
03/2005
1Pulmonary Hypertension
03/2005
1Autoimmune Hepatitis
01/2005
1Chronic Hepatitis (Chronic Active Hepatitis)
11/2004
1Lichen Planus (Lichen Ruber Planus)
11/2004
1Sarcoidosis (Schaumann Disease)
11/2004
1Liver Diseases (Liver Disease)
09/2002
1Paraneoplastic Syndromes (Paraneoplastic Syndrome)
09/2002
1Diarrhea
09/2002
1Multiple Sclerosis
06/2002
1Allergic Contact Dermatitis
05/2002
1Male Breast Neoplasms (Male Breast Cancer)
03/2002

Drug/Important Bio-Agent (IBA)

8InterferonsIBA
02/2011 - 06/2002
5AntigensIBA
02/2011 - 09/2005
5Ribavirin (Virazole)FDA LinkGeneric
02/2011 - 11/2004
4Transforming Growth Factor beta (TGF-beta)IBA
01/2012 - 05/2008
4Matrix Metalloproteinases (MMPs)IBA
08/2005 - 02/2002
3AutoantibodiesIBA
08/2011 - 10/2004
3LY2109761IBA
07/2011 - 10/2009
3CytokinesIBA
04/2011 - 01/2009
3IntegrinsIBA
08/2010 - 01/2002
3Antiviral Agents (Antivirals)IBA
07/2010 - 11/2004
3Tissue Inhibitor of Metalloproteinase-2IBA
05/2004 - 02/2002
2Extracellular Matrix ProteinsIBA
08/2011 - 09/2003
2Transforming Growth Factor beta1 (TGF beta 1)IBA
02/2010 - 07/2002
2Transforming Growth Factors (Transforming Growth Factor)IBA
03/2009 - 05/2008
2Hormones (Hormone)IBA
01/2009 - 09/2002
2Biological ProductsIBA
01/2009 - 09/2002
2KalininIBA
12/2007 - 09/2003
2Interferon-alpha2bIBA
05/2006 - 08/2005
2Adrenal Cortex Hormones (Corticosteroids)IBA
01/2005 - 10/2004
1AcidsIBA
09/2011
1Protein Isoforms (Isoforms)IBA
04/2011
1RNA (Ribonucleic Acid)IBA
02/2011
1DNA (Deoxyribonucleic Acid)IBA
02/2011
1EnzymesIBA
08/2010
1ADAM ProteinsIBA
08/2010
1Transforming Growth Factor beta Receptors (TGF beta Receptors)IBA
02/2010
1Connective Tissue Growth FactorIBA
02/2010
1Sorafenib (BAY 43-9006)FDA Link
10/2009
1Phosphotransferases (Kinase)IBA
10/2009
1Transforming Growth Factor-beta Type I ReceptorIBA
10/2009
1Integrin beta1IBA
03/2009
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2009
1Cadherins (E-Cadherin)IBA
05/2008
1Biomarkers (Surrogate Marker)IBA
08/2007
1alpha-Fetoproteins (alpha-Fetoprotein)IBA
08/2007
1Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
08/2007
1Interleukin-1beta (Interleukin 1 beta)IBA
05/2006
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
05/2006
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
02/2006
1vandetanib (ZD6474)IBA
02/2006
1Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
02/2006
1Anti-Bacterial Agents (Antibiotics)IBA
09/2005
1Bosentan (Tracleer)FDA Link
03/2005
1Matrix Metalloproteinase 9 (Gelatinase B)IBA
03/2005
1Interferon-alpha (Interferon Alfa)IBA
11/2004
1eIF-2 Kinase (eIF 2 Kinase)IBA
11/2004
1Proteins (Proteins, Gene)FDA Link
11/2004
1Tissue Inhibitor of Metalloproteinase-1IBA
05/2004
1progelatinaseIBA
05/2004
1Integrin alpha3beta1IBA
07/2002
1Peptide Hydrolases (Proteases)FDA Link
03/2002
1GelatinasesIBA
03/2002
1Matrix Metalloproteinase 14 (MT1-MMP)IBA
02/2002
1Matrix Metalloproteinase 2 (Gelatinase A)IBA
02/2002

Therapy/Procedure

9Therapeutics
02/2011 - 09/2002
1Length of Stay
09/2005